Not So Intelligent Design

McGill University researchers have discovered how the enzyme Caspase-12 shuts down human immune system. Apparently 20% of people of African descent have a gene to produce this enzyme.

Caspase-12 is found in around 20% of people of African descent, but was entirely lost from all other ethnicities around 60,000 years ago.

Capase-12 blocks an enzyme involved in inflamation.

"It's possible that in Africa the protein could once have had a protective function fighting autoimmune diseases or perhaps parasites, like malaria; today caspase-12 provides no benefit to those who carry it, and often leaves the body more vulnerable to life-threatening infections and sepsis ('septic shock').

Sounds like the kind of thing that would happen if an organism were in the process of evolving and had not quite gotten there yet.

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One Response to “Not So Intelligent Design”

  1. Guess Who Says:

    Clearly we don’t talk to each other enough anymore. Caspases are proteins involved in apoptosis, which is what my research focuses on. I can diagram this type of programmed cell death pathway for you and your readers if you would like, but I imagine that quarks are more your speed…

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